Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19444729 | 0.84 | HRH3 (0.46) | ALDH1A1HRH3HRH4LMNAMAPT | |
| SCHEMBL3123680 | 0.76 | HRH3 (0.69) | ALDH1A1HRH3HRH4LMNAMAPT | |
| SCHEMBL13285102 | 0.75 | SLC6A4 (0.48) | ALDH1A1LMNAMAPTCYP2D6SLC6A2 | |
| SCHEMBL3130725 | 0.74 | KDM4E (0.72) | ALDH1A1HRH3HRH4KDM4EHTT | |
| SCHEMBL13644118 | 0.71 | LOXL2 (0.42) | ALDH1A1HRH3HRH4LMNAMAPT | |
| SCHEMBL10527983 | 0.69 | AOC3 (0.35) | ALDH1A1MAPTSMN1; SMN2AOC3JAK3 | |
| SCHEMBL22087276 | 0.68 | OPRL1 (0.40) | LMNAAOC3DYRK1AKCNH2AOC1 | |
| SCHEMBL11620447 | 0.68 | CYP2D6 (0.54) | ALDH1A1HRH3HRH4LMNAMAPT | |
| SCHEMBL12082363 | 0.67 | HRH3 (0.77) | ALDH1A1HRH3HRH4LMNAMAPT | |
| SCHEMBL365219 | 0.67 | ALDH1A1 (0.55) | ALDH1A1HRH3HRH4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604281-A1 | 2(1H)-QUINOLINONE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-02-05 | — | — | EP | disclosed |