SCHEMBL2168159

SCHEMBL2168159

C=CCCC[SiH](Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KCNA3 P22001 1/20 0.34
ESR1 P03372 1/20 0.32
USP2 O75604 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
THRB P10828 1/20 0.31
TLR8 Q9NR97 1/20 0.30
LMNA P02545 1/20 0.30
LTA4H P09960 1/20 0.30
TSHR P16473 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1781213 0.89 ALDH1A1 (0.39) ALDH1A1L3MBTL1KCNA3KDM4EMEN1
SCHEMBL1782417 0.76 THRB (0.38) ALDH1A1L3MBTL1KCNA3KDM4EMEN1
SCHEMBL9498549 0.75 ALDH1A1 (0.45) ALDH1A1L3MBTL1KCNA3ESR1USP2
SCHEMBL706800 0.75 LTA4H (0.47) ALDH1A1KCNA3ESR1SMN1; SMN2LMNA
SCHEMBL3350917 0.73 HDAC3 (0.52) KCNA3LTA4HTSHR
SCHEMBL4363258 0.73 KCNA3 (0.37) ALDH1A1KCNA3TDP1LTA4HTSHR
SCHEMBL704670 0.73 DRD2 (0.44) TDP1SMN1; SMN2LTA4H
SCHEMBL19927175 0.73 LTA4H (0.47) ALDH1A1KCNA3ESR1SMN1; SMN2LMNA
SCHEMBL4361022 0.73 KCNA3 (0.41) ALDH1A1KCNA3SMN1; SMN2LTA4HTSHR
SCHEMBL7980722 0.72 ALDH1A1 (0.62) ALDH1A1L3MBTL1KCNA3KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1950239-B1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO LTD (JP) 2017-01-04 EP disclosed
US-7985476-B2 Transparent zirconia dispersion and zirconia particle-containing resin composition, composition for sealing light emitting element and light emitting element, hard coat film and optical functional film and optical component, and method for producing zirconia particle-containing resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2011-07-26 US disclosed
US-20090140284-A1 Transparent Inorganic Oxide Dispersion and Iorganic Oxide Particle-Containing Resin Composition, Composition for Sealing Light Emitting Element and Light Emitting element, Hard Coat Film and Optical Functional Film and Optical Component, and Method for Producing Inorganic Oxide Pariticle-Containing Resin SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2009-06-04 US disclosed
EP-1950239-A1 TRANSPARENT INORGANIC-OXIDE DISPERSION, RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES, COMPOSITION FOR ENCAPSULATING LUMINESCENT ELEMENT, LUMINESCENT ELEMENT, HARD COAT, OPTICAL FUNCTIONAL FILM, OPTICAL PART, AND PROCESS FOR PRODUCING RESIN COMPOSITION CONTAINING INORGANIC OXIDE PARTICLES SUMITOMO OSAKA CEMENT CO., LTD. (JP) 2008-07-30 EP disclosed