SCHEMBL2168339

SCHEMBL2168339

O=C(Nc1ccc(-c2ccccc2)c(Cl)c1)c1cc(Cl)cc(-c2ccccc2)c1O

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.60
TBXAS1 P24557 1/20 0.60
MAPK1 P28482 1/20 0.60
PTGS2 P35354 1/20 0.60
MAPK14 Q16539 1/20 0.60
STK39 Q9UEW8 13/20 0.58
PARG Q86W56 4/20 0.58
TP53 P04637 1/20 0.51
ACLY P53396 1/20 0.51
PNLIP P16233 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887950 1.00 PTGS1 (0.60) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL30887948 0.88 STK39 (0.57) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL2167171 0.88 STK39 (0.57) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL30887941 0.82 ACLY (0.58) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL2168262 0.82 ACLY (0.58) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL7742767 0.80 P2RX1 (0.64) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL6287443 0.77 RORC (0.58)
SCHEMBL9868077 0.77 STK39 (0.77) PTGS1TBXAS1MAPK1PTGS2MAPK14
SCHEMBL9769768 0.76 PTPN1 (0.71)
3,3',4',5-Tetrachlorosalicylanilide SCHEMBL29367227 0.76 PTGS1 (1.00) PTGS1TBXAS1MAPK1PTGS2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3653303-B1 PIPETTE TIP RACK BIOTIX INC (US) 2025-02-26 EP disclosed
US-12201987-B2 Pipette tip rack BIOTIX, INC. (US) 2025-01-21 US disclosed
EP-4376673-B1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B V (NL) 2025-01-01 EP disclosed
EP-4376673-A1 FILAMENTS FOR ORAL CARE IMPLEMENTS Unilever IP Holdings B.V. (NL) 2024-06-05 EP disclosed
CN-118042960-A Filaments for oral care implements 联合利华知识产权控股有限公司 2024-05-14 CN disclosed
US-11590490-B2 Pipette tips BIOTIX, INC. (US) 2023-02-28 US disclosed
WO-2023006359-A1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B.V. (NL) 2023-02-02 WO disclosed
EP-3628404-B1 PIPETTE TIP TRAYS BIOTIX INC (US) 2021-06-30 EP disclosed
EP-3831489-A1 PIPETTE TIPS Biotix, Inc. (US) 2021-06-09 EP disclosed
US-20210039086-A1 PIPETTE TIPS BIOTIX, INC. 2021-02-11 US disclosed
EP-1458419-B1 ANTIMICROBIAL CONTACT LENS CASE NOVARTIS AG (CH) 2005-05-04 EP disclosed
EP-1458419-A1 ANTIMICROBIAL CONTACT LENS CASE Novartis AG (CH) 2004-09-22 EP disclosed
US-20030176530-A1 Antimicrobial contact lens case LINDLEY KAREN FRANCES (US) 2003-09-18 US disclosed
WO-2003049776-A1 ANTIMICROBIAL CONTACT LENS CASE NOVARTIS AG (CH) 2003-06-19 WO disclosed
US-20030108761-A1 Anti-bacterial paper products EDDLEMON TAMMY (US) 2003-06-12 US disclosed
WO-2001070189-A1 METHOD AND COMPOSITION FOR SKIN LIGHTENING APPLYING CARBOXYLIC ACIDS UNILEVER PLC (GB) 2001-09-27 WO disclosed
US-6138315-A Antimicrobial active compounds CHESEBROUGH-POND'S USA CO., DIVISON OF CONOPCO, INC. (US) 2000-10-31 US disclosed
US-5919152-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1999-07-06 US disclosed
US-5846215-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-12-08 US disclosed
US-4022880-A ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS LEVER BROTHERS COMPANY (US) 1977-05-10 US disclosed