SCHEMBL2168262

SCHEMBL2168262

O=C(Nc1ccccc1Cl)c1cc(Cl)cc(-c2ccccc2)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 6/20 0.58
CYP1A2 P05177 1/20 0.56
HPGD P15428 1/20 0.56
CYP2C19 P33261 1/20 0.56
STK39 Q9UEW8 5/20 0.54
EPHB3 P54753 1/20 0.49
PTGS1 P23219 1/20 0.48
TBXAS1 P24557 1/20 0.48
MAPK1 P28482 1/20 0.48
PTGS2 P35354 1/20 0.48
MAPK14 Q16539 1/20 0.48
PARG Q86W56 1/20 0.47
MAPT P10636 2/20 0.47
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47
CASP3 P42574 1/20 0.47
ATM Q13315 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887941 1.00 ACLY (0.58) ACLYCYP1A2HPGDCYP2C19STK39
SCHEMBL2168339 0.82 PTGS1 (0.60) ACLYSTK39PTGS1TBXAS1MAPK1
SCHEMBL30887950 0.82 PTGS1 (0.60) ACLYSTK39PTGS1TBXAS1MAPK1
SCHEMBL7100072 0.80 HPGD (0.63) CYP1A2HPGDCYP2C19EPHB3MAPT
SCHEMBL2167171 0.79 STK39 (0.57) CYP2C19STK39PTGS1TBXAS1MAPK1
SCHEMBL30887948 0.79 STK39 (0.57) CYP2C19STK39PTGS1TBXAS1MAPK1
SCHEMBL9769768 0.77 PTPN1 (0.71) HPGDMAPTALDH1A1MEN1KMT2A
SCHEMBL16147455 0.77 KCNMA1 (0.71) CYP1A2HPGDCYP2C19MAPK1MAPT
SCHEMBL31093979 0.77 KCNMA1 (0.71) CYP1A2HPGDCYP2C19MAPK1MAPT
SCHEMBL17413298 0.76 RAB9A (0.66) ACLYSTK39MAPTNPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3653303-B1 PIPETTE TIP RACK BIOTIX INC (US) 2025-02-26 EP disclosed
US-12201987-B2 Pipette tip rack BIOTIX, INC. (US) 2025-01-21 US disclosed
EP-4376673-B1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B V (NL) 2025-01-01 EP disclosed
EP-4376673-A1 FILAMENTS FOR ORAL CARE IMPLEMENTS Unilever IP Holdings B.V. (NL) 2024-06-05 EP disclosed
CN-118042960-A Filaments for oral care implements 联合利华知识产权控股有限公司 2024-05-14 CN disclosed
US-11590490-B2 Pipette tips BIOTIX, INC. (US) 2023-02-28 US disclosed
WO-2023006359-A1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B.V. (NL) 2023-02-02 WO disclosed
EP-3628404-B1 PIPETTE TIP TRAYS BIOTIX INC (US) 2021-06-30 EP disclosed
EP-3831489-A1 PIPETTE TIPS Biotix, Inc. (US) 2021-06-09 EP disclosed
US-20210039086-A1 PIPETTE TIPS BIOTIX, INC. 2021-02-11 US disclosed
WO-2010008737-A2 ANTIMICROBIAL FLUID HANDLING DEVICES AND METHODS OF MANUFACTURE PELICAN GROUP HOLDINGS, INC. (US) 2010-01-21 WO disclosed
US-20070089847-A1 Anti-microbial paper products having a substituted 1,2-dihydroquinoline NOVUS INTERNATIONAL, INC. (US) 2007-04-26 US disclosed
WO-2007044398-A2 ANTI-MICROBIAL PAPER PRODUCTS HAVING A SUBSTITUTED 1,2-DIHYDROQUINOLINE NOVUS INTERNATIONAL INC. (US) 2007-04-19 WO disclosed
EP-1458419-B1 ANTIMICROBIAL CONTACT LENS CASE NOVARTIS AG (CH) 2005-05-04 EP disclosed
US-20030176530-A1 Antimicrobial contact lens case LINDLEY KAREN FRANCES (US) 2003-09-18 US disclosed
US-20030108761-A1 Anti-bacterial paper products EDDLEMON TAMMY (US) 2003-06-12 US disclosed
US-6138315-A Antimicrobial active compounds CHESEBROUGH-POND'S USA CO., DIVISON OF CONOPCO, INC. (US) 2000-10-31 US disclosed
US-5919152-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1999-07-06 US disclosed
US-5846215-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-12-08 US disclosed
US-4022880-A ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS LEVER BROTHERS COMPANY (US) 1977-05-10 US disclosed