SCHEMBL21534010

SCHEMBL21534010

CCSC(C)c1cncc2c(OCC3CC3)c(F)ccc12

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ALOX5AP P20292 3/20 0.33
▸ FEN1 P39748 3/20 0.33
▸ FFAR4 Q5NUL3 1/20 0.32
▸ CHUK O15111 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21690530 0.77 FFAR4 (0.38) ALOX5APFEN1FFAR4CHUK
SCHEMBL20204677 0.77 PDE2A (0.37) ALOX5APFEN1FFAR4CHUK
SCHEMBL21325058 0.74 FFAR4 (0.35) ALOX5APFEN1FFAR4CHUK
SCHEMBL21325059 0.66 PDE3B (0.35) ALOX5APFEN1FFAR4CHUK
SCHEMBL21325056 0.66 ALOX5AP (0.34) ALOX5APFEN1FFAR4
SCHEMBL21690528 0.65 RIPK1 (0.38) ALOX5APFEN1FFAR4
SCHEMBL20207783 0.65 ALOX5AP (0.32) ALOX5APFEN1CHUK
SCHEMBL20376461 0.64 CYP1A2 (0.38) ALOX5APFEN1
SCHEMBL21690529 0.64 ALOX5AP (0.34) ALOX5APFEN1FFAR4
SCHEMBL24180121 0.63 ALOX5AP (0.34) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190330210-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2019-10-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190330210-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS DUT, TYMP, DPYD ALOX5AP 2919/4885FEN1 108/4885FFAR4 4718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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