Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21756935 | 0.84 | LMNA (0.59) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL4905949 | 0.78 | TSHR (0.57) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL31618874 | 0.77 | TYR (0.57) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL950881 | 0.77 | TYR (0.57) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL15452247 | 0.77 | TYR (0.57) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL1349872 | 0.77 | PDE2A (0.42) | ADRA1AGABRA1GABRB2GABRB1PDE2A | |
| SCHEMBL19028073 | 0.76 | PTGS2 (0.45) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL20928551 | 0.76 | ALOX15 (0.44) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL6152512 | 0.74 | CASP1 (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL30809607 | 0.74 | CA3 (0.48) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3605091-A1 | KIT, METHOD AND REAGENT FOR MEASURING MEASUREMENT TARGET SUBSTANCE | FUJIFILM Corporation (JP) | 2020-02-05 | — | — | EP | disclosed |