SCHEMBL22068587

SCHEMBL22068587

c1ccc2c(c1)Oc1ccccc1C2c1ccncc1-c1cnccc1N1c2ccccc2Oc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.36
CYP2C9 P11712 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ATM Q13315 1/20 0.32
LMNA P02545 2/20 0.31
TSHR P16473 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
TP53 P04637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21693057 0.86 P2RX4 (0.37) MAOAMAOBHTTNPSR1
SCHEMBL17952929 0.77 MAOA (0.42) ALDH1A1MAOAMAOBKDM4EHTT
SCHEMBL17952761 0.77 HTR2A (0.36) CYP2C9KMT2AALDH1A1LMNAKDM4E
SCHEMBL17952763 0.76 ADRA1A (0.39) CYP2C9MEN1KMT2AALDH1A1LMNA
SCHEMBL17952760 0.76 CYP1A2 (0.38) ALDH1A1MAOA
SCHEMBL17952722 0.74 P2RX4 (0.37) MAOAMAOBHTTNPSR1
SCHEMBL21396792 0.72 CYP11B2 (0.37)
SCHEMBL21927334 0.69 ATR (0.36) MEN1KMT2AALDH1A1MAOAMAOB
SCHEMBL29534495 0.69 MGLL (0.40) ALDH1A1TSHRMAPK1HTTTP53
SCHEMBL21922119 0.69 NPC1 (0.43) ALDH1A1LMNATSHRKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247771-B1 PYRIDINES AND DERIVATIVES THEREOF AS COMPONENTS FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2020-06-10 EP disclosed