Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16020861 | 0.85 | THRA (0.34) | THRBTHRASMN1; SMN2GAAMEN1 | |
| SCHEMBL21697575 | 0.84 | THRB (0.38) | THRBTHRASMN1; SMN2GAAMAPT | |
| SCHEMBL21697612 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTHPGDKDM4ETDP1 | |
| SCHEMBL16018689 | 0.80 | ALOX5 (0.40) | GAA | |
| SCHEMBL20741824 | 0.80 | ABCB1 (0.41) | THRBSMN1; SMN2GAAMAPTHPGD | |
| SCHEMBL21697537 | 0.77 | MRGPRX4 (0.36) | SMN1; SMN2DRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21697653 | 0.77 | CYP2A6 (0.40) | THRBTHRASMN1; SMN2GAAMAPT | |
| SCHEMBL21697645 | 0.76 | HTR2A (0.37) | SMN1; SMN2MEN1KMT2ADRD1SLC6A2 | |
| SCHEMBL16018597 | 0.73 | ALOX5 (0.40) | GAA | |
| SCHEMBL21697564 | 0.73 | FFAR1 (0.37) | SMN1; SMN2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968258-B1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-12 | — | — | EP | disclosed |