SCHEMBL21703736

SCHEMBL21703736

C/C=C\C1=C(c2ccccc2)c2ccccc2C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.35
MAOA P21397 2/20 0.34
CASP6 P55212 1/20 0.34
KDR P35968 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
MIF P14174 1/20 0.33
MAOB P27338 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
BCHE P06276 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20006496 0.77 MAOA (0.38) MAOACASP6MIFMAOBALDH1A1
SCHEMBL24223383 0.77 MAOA (0.38) MAOACASP6MIFMAOBALDH1A1
SCHEMBL27837652 0.73 MTNR1A (0.41) PTGS2MAOAKDRADORA2AADORA1
SCHEMBL19089891 0.72 MAOA (0.34) MAOACASP6MIFMAOBALDH1A1
SCHEMBL19178623 0.72 MAOA (0.34) MAOACASP6MIFMAOBALDH1A1
SCHEMBL11546612 0.72 MAOA (0.40) PTGS2MAOAKDRADORA2AADORA1
SCHEMBL16139564 0.70 CES1 (0.44) MAOAMTNR1AMTNR1BMIFMAOB
SCHEMBL27837653 0.70 MTNR1A (0.39) PTGS2MAOAMTNR1AMTNR1BALDH1A1
SCHEMBL9764142 0.70 PTGS2 (0.51) PTGS2MAOACASP6ESR1ESR2
SCHEMBL132494 0.70 ESR2 (0.59) PTGS2MAOAKDRADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032574-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-02-13 WO disclosed