SCHEMBL20006496

SCHEMBL20006496

C/C=C\C1=C(/C=C\C)c2ccccc2C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.38
BCHE P06276 1/20 0.35
CES1 P23141 1/20 0.35
KDM4E B2RXH2 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 5/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOB P27338 2/20 0.33
MIF P14174 1/20 0.33
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP2 O95551 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19089891 0.87 MAOA (0.34) MAOABCHECES1KDM4EMEN1
SCHEMBL19178623 0.87 MAOA (0.34) MAOABCHECES1KDM4EMEN1
SCHEMBL26973741 0.82 ALDH1A1 (0.35) MAOAALDH1A1NPC1RAB9AADRA2A
SCHEMBL26442866 0.81 ALDH1A1 (0.46) KDM4EALDH1A1LMNAHPGDCYP1A2
SCHEMBL24223383 0.81 MAOA (0.38) MAOABCHECES1KDM4EMEN1
SCHEMBL19784985 0.81 MAOA (0.38) MAOABCHECES1KDM4EMEN1
SCHEMBL25044503 0.77 ALDH1A1 (0.41) MAOAKDM4EMEN1KMT2AALDH1A1
SCHEMBL21703736 0.77 PTGS2 (0.35) MAOABCHECES1KDM4EMEN1
SCHEMBL20115446 0.69 MAOA (0.34) MAOABCHECES1KDM4EALDH1A1
SCHEMBL24469350 0.69 MAOA (0.34) MAOABCHECES1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230028822-A1 PHOTOSENSITIVE INK COMPOSITION, CURED PRODUCT, DISPLAY PANEL, AND METHOD FOR PRODUCING CURED PRODUCT TOKYO OHKA KOGYO CO., LTD. (JP) 2023-01-26 US disclosed
US-11056652-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2021-07-06 US disclosed
US-20200139433-A1 METHOD FOR PRODUCING SURFACE-MODIFIED METAL OXIDE FINE PARTICLE, METHOD FOR PRODUCING IMPROVED METAL OXIDE FINE PARTICLES, SURFACE-MODIFIED METAL OXIDE FINE PARTICLES, AND METAL OXIDE FINE PARTICLE DISPERSION LIQUID TOKYO OHKA KOGYO CO., LTD. (JP) 2020-05-07 US disclosed
US-20190288209-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-09-19 US disclosed
US-10416560-B2 Coloring agent dispersion, photosensitive resin composition, cured product, organic el element, method for forming pattern, and method for producing photosensitive resin composition TOKYO OHKA KOGYO CO, LTD. (JP) 2019-09-17 US disclosed
US-10355217-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2019-07-16 US disclosed
US-10023540-B2 Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element TOKYO OHKA KOGYO CO., LTD. (JP) 2018-07-17 US disclosed
US-9981914-B2 2018-05-29 US disclosed
US-20180113383-A1 COLORING AGENT DISPERSION, PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, ORGANIC EL ELEMENT, METHOD FOR FORMING PATTERN, AND METHOD FOR PRODUCING PHOTOSENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2018-04-26 US disclosed
US-20180086717-A1 HYDROGEN BARRIER AGENT, HYDROGEN BARRIER FILM FORMING COMPOSITION, HYDROGEN BARRIER FILM, METHOD FOR PRODUCING HYDROGEN BARRIER FILM, AND ELECTRONIC ELEMENT TOKYO OHKA KOGYO CO., LTD. (JP) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10355217-B2 Compounds and organic electronic devices ETV6, AFF2, CYP2C19 MAOA 287/4885BCHE 2009/4885CES1 2596/4885
US-11056652-B2 Compounds and organic electronic devices ETV6, AFF2, CYP2C19 MAOA 287/4885BCHE 2009/4885CES1 2596/4885
US-20190288209-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, AFF2, CYP2C19 MAOA 287/4885BCHE 2009/4885CES1 2596/4885
US-20180086717-A1 HYDROGEN BARRIER AGENT, HYDROGEN BARRIER FILM FORMING COMPOSITION, HYDROGEN BARRIER FILM, METHOD FOR PRODUCING HYDROGEN BARRIER FILM, AND ELECTRONIC ELEMENT SLC9A2, SLC9A1, NHERF1 MAOA 556/4885BCHE 802/4885CES1 4043/4885
US-10023540-B2 Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing hydrogen barrier film, and electronic element SLC9A2, SLC9A1, NHERF1 MAOA 556/4885BCHE 802/4885CES1 4043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.