Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708707 | 0.89 | CCR1 (0.36) | CCR1KMT2AADRB1LMNA | |
| SCHEMBL21708512 | 0.85 | CCR1 (0.36) | CCR1KMT2ALMNA | |
| SCHEMBL21708545 | 0.85 | KMT2A (0.33) | KMT2AADRB1 | |
| SCHEMBL21708723 | 0.85 | RIPK1 (0.36) | KMT2ALMNA | |
| SCHEMBL21708561 | 0.84 | CCR1 (0.30) | CCR1KMT2A | |
| SCHEMBL21708518 | 0.82 | TAS1R3 (0.32) | KMT2A | |
| SCHEMBL21708548 | 0.82 | MEN1 (0.35) | KMT2ALMNA | |
| SCHEMBL21708464 | 0.81 | PTGFR (0.35) | PTGFR | |
| SCHEMBL21656349 | 0.81 | CTSS (0.35) | CCR1PTGFRKMT2A | |
| SCHEMBL21631958 | 0.80 | PTGFR (0.39) | CCR1PTGFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |