Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.38 |
| ▸ | F2 | P00734 | 7/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708787 | 0.87 | HPGD (0.39) | F10F2PRSS1GABBR2GABBR1 | |
| SCHEMBL21708681 | 0.86 | L3MBTL1 (0.46) | TAS1R3TAS1R1ROCK2GAA | |
| SCHEMBL21708638 | 0.85 | GABBR2 (0.38) | F10F2GABBR2GABBR1GAA | |
| SCHEMBL21708758 | 0.81 | ROCK2 (0.45) | TAS1R3TAS1R1ROCK2PSEN1PSEN2 | |
| SCHEMBL21708755 | 0.80 | KMT2A (0.38) | TAS1R3TAS1R1GAAPSEN1PSEN2 | |
| SCHEMBL21708766 | 0.78 | GABBR2 (0.33) | F10F2GABBR2GABBR1ROCK2 | |
| SCHEMBL21708792 | 0.78 | TAS1R3 (0.33) | F10F2PRSS1GABBR2GABBR1 | |
| SCHEMBL21656318 | 0.76 | GABBR2 (0.42) | F10F2PRSS1GABBR2GABBR1 | |
| SCHEMBL23750383 | 0.75 | GABBR2 (0.49) | GABBR2GABBR1ROCK2GAACYP1A2 | |
| SCHEMBL23750224 | 0.75 | GABBR2 (0.49) | GABBR2GABBR1ROCK2GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |