Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708643 | 0.83 | POLB (0.45) | TAS1R3TAS1R1HTTMEN1KMT2A | |
| SCHEMBL21708763 | 0.82 | S1PR1 (0.35) | PTGFRRAB9ANPC1TAS1R3TAS1R1 | |
| SCHEMBL21708665 | 0.80 | GAA (0.38) | RAB9AMEN1MAPTKMT2AGAA | |
| SCHEMBL21708747 | 0.79 | TAS1R3 (0.36) | PTGFRRAB9ANPC1TAS1R3TAS1R1 | |
| SCHEMBL21631944 | 0.79 | GAA (0.50) | PTGFRHTTMEN1MAPTKMT2A | |
| SCHEMBL21656117 | 0.78 | RAB9A (0.36) | PTGFRRAB9ANPC1HTTGAA | |
| Hydrochloric Acid SCHEMBL21708784 | 0.78 | GAA (0.37) | PTGFRTAS1R3TAS1R1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL21708730 | 0.76 | CTDSP1 (0.36) | PTGFRRAB9AHTTMEN1KMT2A | |
| SCHEMBL21708590 | 0.75 | L3MBTL1 (0.41) | RAB9ATAS1R3TAS1R1HTTMEN1 | |
| SCHEMBL21708792 | 0.72 | TAS1R3 (0.33) | TAS1R3TAS1R1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |