Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | USP9X | Q93008 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708759 | 0.83 | NPC1 (0.32) | PLCG1NPC1RAB9AANO1KMT2A | |
| SCHEMBL21708779 | 0.81 | NPC1 (0.33) | NPC1RAB9AANO1KMT2AGAA | |
| SCHEMBL21708691 | 0.79 | LMNA (0.36) | RAB9AKMT2AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL21656559 | 0.78 | PLCG1 (0.39) | PLCG1SMN1; SMN2TDP1KDM4EPRSS1 | |
| SCHEMBL21708790 | 0.75 | NPC1 (0.32) | NPC1RAB9AANO1KMT2AALDH1A1 | |
| SCHEMBL21708674 | 0.75 | ADRB2 (0.33) | KMT2AMEN1L3MBTL1PRSS1CTSG | |
| SCHEMBL21631946 | 0.74 | SLC22A12 (0.38) | PLCG1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL21708762 | 0.72 | KMT2A (0.37) | NPC1RAB9AKMT2AMEN1GAA | |
| SCHEMBL21708795 | 0.69 | TAS1R3 (0.33) | ALDH1A1 | |
| SCHEMBL31368866 | 0.67 | KMT2A (0.33) | NPC1RAB9AKMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |