Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 9/20 | 0.73 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.73 |
| ▸ | FNTA | P49354 | 1/20 | 0.65 |
| ▸ | FNTB | P49356 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | RNF4 | P78317 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703396 | 0.87 | RNF4 (0.73) | MTNR1BMTNR1AFNTAFNTBL3MBTL1 | |
| SCHEMBL31703433 | 0.86 | FNTA (0.62) | MTNR1BMTNR1AFNTAFNTBL3MBTL1 | |
| SCHEMBL11645642 | 0.86 | FNTA (0.62) | MTNR1BMTNR1AFNTAFNTBRNF4 | |
| SCHEMBL2171671 | 0.85 | L3MBTL1 (0.68) | MTNR1BMTNR1AFNTAFNTBL3MBTL1 | |
| SCHEMBL8142314 | 0.84 | MTNR1B (1.00) | MTNR1BMTNR1AL3MBTL1TSHRHPGD | |
| SCHEMBL31704006 | 0.84 | MTNR1B (0.71) | MTNR1BMTNR1AFNTAFNTBHPGD | |
| SCHEMBL2173035 | 0.84 | MTNR1A (0.73) | MTNR1BMTNR1AL3MBTL1TSHRHPGD | |
| SCHEMBL11827952 | 0.82 | ALDH1A1 (0.57) | MTNR1BMTNR1AFNTAFNTBSMN1; SMN2 | |
| SCHEMBL4126168 | 0.79 | RAB9A (0.67) | L3MBTL1TSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11648371 | 0.78 | XIAP (0.63) | MTNR1BMTNR1AFNTAFNTBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |