Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170564 | 0.86 | HSD17B3 (0.48) | FFAR4HTR6SMN1; SMN2MAPTTP53 | |
| SCHEMBL2170768 | 0.85 | ESR1 (0.45) | FFAR4HTR6SMN1; SMN2MAPTTP53 | |
| SCHEMBL2170359 | 0.84 | MAPT (0.48) | FFAR4HTR6MAPTLMNA | |
| SCHEMBL2170067 | 0.84 | CCNT1 (0.50) | HTR6SMN1; SMN2MAPTLMNA | |
| SCHEMBL2171609 | 0.83 | HTR6 (0.46) | HTR6DRD2DRD3KCNH2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2169494 | 0.83 | CCNT1 (0.49) | HTR6SMN1; SMN2MAPTLMNA | |
| SCHEMBL2236877 | 0.81 | HTR6 (0.40) | FFAR4HTR6DRD2DRD3KCNH2 | |
| SCHEMBL2170559 | 0.77 | SLC22A12 (0.47) | HTR6MAPTLMNA | |
| SCHEMBL2171757 | 0.77 | ESR1 (0.47) | FFAR4SMN1; SMN2MAPTHDAC1HDAC4 | |
| SCHEMBL26536689 | 0.76 | FFAR4 (0.63) | FFAR4DRD2DRD3KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | claimed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | claimed |
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | disclosed |