Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172302 | 0.70 | HSD11B1 (0.38) | RAB9AMAPTHTTALDH1A1KMT2A | |
| SCHEMBL2171361 | 0.69 | ALDH1A1 (0.40) | ALDH1A1POLBGAA | |
| SCHEMBL2169501 | 0.68 | POLB (0.36) | RAB9ASMN1; SMN2MAPTHTTCYP2C19 | |
| SCHEMBL2170751 | 0.68 | OPRM1 (0.38) | SMN1; SMN2HTTPOLBGAANPC1 | |
| SCHEMBL2169321 | 0.68 | ROCK2 (0.51) | RAB9ASMN1; SMN2KDM4EMAPTHTT | |
| Hydrochloric Acid SCHEMBL9701760 | 0.68 | RAB9A (0.70) | RAB9ASMN1; SMN2KDM4EMAPTHTT | |
| SCHEMBL2169266 | 0.67 | HTT (0.41) | RAB9ASMN1; SMN2KDM4EMAPTHTT | |
| SCHEMBL26319974 | 0.66 | CYP1A2 (0.51) | RAB9ASMN1; SMN2KDM4ECYP1A2CYP2C19 | |
| SCHEMBL2170189 | 0.66 | ROCK1 (0.36) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL895535 | 0.65 | HIF1A (0.49) | RAB9ASMN1; SMN2KDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183978-A1 | Phenylpyri(mi)dinylazoles | PIR, PIN4, PNN | RAB9A 3531/4885SMN1; SMN2 4583/4885KDM4E 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.