SCHEMBL21718110

SCHEMBL21718110

CC(C)c1ccc(-c2ccc3c(c2)c2cc4ccccc4c4c5ccccc5n3c24)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.35
DHODH Q02127 2/20 0.33
TNKS O95271 1/20 0.33
PARP1 P09874 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PARP2 Q9UGN5 1/20 0.33
RORA P35398 1/20 0.32
RORC P51449 1/20 0.32
RORB Q92753 1/20 0.32
CASR P41180 4/20 0.32
TSPO P30536 1/20 0.32
PTPN5 P54829 1/20 0.32
EGFR P00533 1/20 0.31
MET P08581 1/20 0.31
PTGES O14684 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22858285 0.95 PIK3CD (0.35) PIK3CDDHODHTNKSPARP1TNKS2
SCHEMBL22679812 0.90 RORA (0.40) RORARORCRORBKDM4EALDH1A1
SCHEMBL21710662 0.88 NTSR1 (0.32) PIK3CDTSPO
SCHEMBL21717841 0.87 TSPO (0.38) TSPOPTGESKDM4EALDH1A1MAPT
SCHEMBL21717407 0.87 TSPO (0.38) TSPOPTGESKDM4EALDH1A1MAPT
SCHEMBL21717830 0.86 TSPO (0.33) PIK3CDDHODHTSPOPTGESAKR1B1
SCHEMBL22858128 0.84 RORA (0.37) TNKS2PARP2RORARORCRORB
SCHEMBL21718108 0.84 TSPO (0.36) TSPOPTGESKDM4EALDH1A1MAPT
SCHEMBL21718109 0.84 TSPO (0.36) TSPOPTGESKDM4E
SCHEMBL21710664 0.84 PTGES (0.32) TSPOPTGESALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed
US-20210005826-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO., LTD. (JP) 2021-01-07 US disclosed
US-20200365812-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2020-11-19 US disclosed
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE LEF1, L1CAM, ESR2 PIK3CD 3864/4885DHODH 3330/4885TNKS 3652/4885
US-20210005826-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC APPARATUS EML4, EBPL, LEF1 PIK3CD 4476/4885DHODH 644/4885TNKS 4428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.