Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723904 | 0.79 | LMNA (0.31) | LMNAHPGD | |
| SCHEMBL21723841 | 0.75 | LMNA (0.41) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL21723869 | 0.75 | GRIN1 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL21723523 | 0.75 | MEN1 (0.34) | MEN1KMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL21723880 | 0.73 | PTPN1 (0.45) | TP53MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21723614 | 0.72 | KMT2A (0.38) | TP53MEN1KMT2AALDH1A1GAA | |
| SCHEMBL21724332 | 0.71 | RIPK1 (0.44) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL21724865 | 0.71 | KDM4E (0.43) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL21724487 | 0.70 | RIPK1 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21723914 | 0.68 | PYCR1 (0.41) | MEN1KMT2AALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |