Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | IAPP | P10997 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723841 | 0.81 | LMNA (0.41) | LMNA | |
| SCHEMBL21723339 | 0.79 | TP53 (0.35) | LMNAHPGD | |
| SCHEMBL21724332 | 0.76 | RIPK1 (0.44) | LMNA | |
| SCHEMBL21724865 | 0.76 | KDM4E (0.43) | — | |
| SCHEMBL21724535 | 0.74 | PYCR1 (0.46) | — | |
| SCHEMBL21724346 | 0.73 | ALDH1A1 (0.47) | LMNATSHR | |
| SCHEMBL21723914 | 0.72 | PYCR1 (0.41) | LMNATSHR | |
| SCHEMBL21723902 | 0.72 | MTOR (0.38) | HSP90AA1 | |
| SCHEMBL21723556 | 0.72 | PKM (0.33) | LMNAHPGDTSHR | |
| SCHEMBL21723980 | 0.72 | CA2 (0.45) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |