Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724456 | 0.91 | PYCR1 (0.36) | RIPK1MAPK14ARSLC6A2SLC6A4 | |
| SCHEMBL21724804 | 0.79 | DAO (0.43) | RIPK1 | |
| SCHEMBL21723933 | 0.77 | MEN1 (0.46) | RIPK1SLC6A3 | |
| SCHEMBL21724865 | 0.77 | KDM4E (0.43) | RIPK1 | |
| SCHEMBL21724332 | 0.75 | RIPK1 (0.44) | RIPK1MAPK14 | |
| SCHEMBL21724709 | 0.74 | PYCR1 (0.48) | SLC6A2SLC6A4 | |
| SCHEMBL21723776 | 0.73 | — | — | |
| SCHEMBL21723914 | 0.73 | PYCR1 (0.41) | — | |
| SCHEMBL21723841 | 0.73 | LMNA (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21724519 | 0.72 | GAA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |