Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724255 | 0.85 | HSD17B10 (0.46) | KCNH2HTR2ASLC6A4ALDH1A1HSD17B10 | |
| SCHEMBL21723648 | 0.79 | ALDH1A1 (0.48) | TAS2R14ALDH1A1NPSR1DYRK1A | |
| SCHEMBL21724865 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1 | |
| SCHEMBL21724485 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL21723463 | 0.76 | KDM4E (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21724456 | 0.75 | PYCR1 (0.36) | KDM4ESLC6A4NPSR1 | |
| SCHEMBL21724332 | 0.74 | RIPK1 (0.44) | KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL21724709 | 0.74 | PYCR1 (0.48) | KCNH2SLC6A4ALDH1A1NPSR1CYP2D6 | |
| SCHEMBL21724487 | 0.73 | RIPK1 (0.33) | SLC6A4 | |
| SCHEMBL21724519 | 0.72 | GAA (0.41) | KDM4EALDH1A1LMNANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |