Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724487 | 0.91 | RIPK1 (0.33) | MAPK14RIPK1ARSLC6A2SLC6A4 | |
| SCHEMBL21724804 | 0.78 | DAO (0.43) | PYCR1RIPK1NPSR1PKM | |
| SCHEMBL21723933 | 0.76 | MEN1 (0.46) | RIPK1KDM4ESLC6A3 | |
| SCHEMBL21724709 | 0.76 | PYCR1 (0.48) | PYCR1NPSR1SLC6A2SLC6A4 | |
| SCHEMBL21724865 | 0.76 | KDM4E (0.43) | RIPK1ATMKDM4E | |
| SCHEMBL21723625 | 0.75 | PSEN1 (0.41) | KDM4ENPSR1SLC6A4 | |
| SCHEMBL21724332 | 0.74 | RIPK1 (0.44) | P2RX7MAPK14RIPK1KDM4E | |
| SCHEMBL21723914 | 0.72 | PYCR1 (0.41) | PYCR1KDM4EL3MBTL1 | |
| SCHEMBL21723841 | 0.72 | LMNA (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21723776 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | claimed |
| WO-2020035826-A1 | 1,2-DITHIOLONE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |