Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723987 | 0.95 | NPC1 (0.48) | HSD17B10RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL21723934 | 0.86 | NPC1 (0.42) | HSD17B10RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL21723952 | 0.84 | GSK3B (0.41) | HSD17B10RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL21723989 | 0.82 | NPC1 (0.48) | HSD17B10RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL21723978 | 0.80 | HSD17B10 (0.44) | HSD17B10RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL25259095 | 0.79 | KDM4E (0.37) | HSD17B10RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL23452001 | 0.78 | LMNA (0.43) | HSD17B10RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL23451957 | 0.77 | GABRG2 (0.46) | HSD17B10RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL25297318 | 0.76 | NPC1 (0.40) | RAB9ASMN1; SMN2NPC1KDM4EMEN1 | |
| SCHEMBL23452066 | 0.74 | ALDH1A1 (0.53) | HSD17B10RAB9ASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12415813-B2 | Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2025-09-16 | — | — | US | disclosed |
| US-11306103-B2 | Thieno[3,2-b]pyridine-5(4H)-one derivative compound, preparation method thereof and use thereof | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY | 2022-04-19 | — | — | US | disclosed |
| US-11306103-B2 | Thieno[3,2-b]pyridine-5(4H)-one derivative compound, preparation method thereof and use thereof | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY | 2022-04-19 | — | — | US | disclosed |
| US-20210332063-A1 | METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) | 2021-10-28 | — | — | US | disclosed |
| US-20210332063-A1 | METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) | 2021-10-28 | — | — | US | disclosed |
| US-20210171539-A1 | NOVEL THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2021-06-10 | — | — | US | disclosed |
| US-20210171539-A1 | NOVEL THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) | 2021-06-10 | — | — | US | disclosed |
| WO-2020036243-A1 | METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR | 한국해양과학기술원 | 2020-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332063-A1 | METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR | FARS2, CYP4F11, CYP4B1 | HSD17B10 2367/4885RAB9A 3000/4885SMN1; SMN2 4636/4885 |
| US-12415813-B2 | Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor | FARS2, CYP4F11, CYP4B1 | HSD17B10 2367/4885RAB9A 3000/4885SMN1; SMN2 4636/4885 |
| US-20210171539-A1 | NOVEL THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | BRD4, BRPF3, AFF4 | HSD17B10 1772/4885RAB9A 4070/4885SMN1; SMN2 4333/4885 |
| US-11306103-B2 | Thieno[3,2-b]pyridine-5(4H)-one derivative compound, preparation method thereof and use thereof | BRD4, BRPF3, AFF4 | HSD17B10 1574/4885RAB9A 4124/4885SMN1; SMN2 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.