Sugi Predict

Sugi Predict / Compounds / SCHEMBL21723993

SCHEMBL21723993

SCHEMBL21723993

CCN(CC)c1ccc(-c2cc3c(ccc(=O)n3C)s2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.38
▸ MAPT P10636 7/20 0.38
▸ HSD17B10 Q99714 5/20 0.38
▸ L3MBTL1 Q9Y468 5/20 0.38
▸ HPGD P15428 4/20 0.38
▸ MAPK1 P28482 4/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ KDM4E B2RXH2 4/20 0.36
▸ LMNA P02545 2/20 0.36
▸ RAB9A P51151 2/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ THRB P10828 2/20 0.35
▸ POLB P06746 2/20 0.35
▸ BLM P54132 1/20 0.35
▸ GAA P10253 2/20 0.35
▸ RECQL P46063 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21723917 0.80 ALDH1A1 (0.38) ALDH1A1MAPTHSD17B10L3MBTL1HPGD
SCHEMBL21723941 0.79 HSD17B10 (0.44) ALDH1A1MAPTHSD17B10HPGDMAPK1
SCHEMBL21723705 0.77 NPC1 (0.51) ALDH1A1MAPTHSD17B10HPGDMAPK1
SCHEMBL23451965 0.76 ALDH1A1 (0.38) ALDH1A1MAPTHSD17B10L3MBTL1HPGD
SCHEMBL21723978 0.76 HSD17B10 (0.44) ALDH1A1MAPTHSD17B10L3MBTL1HPGD
SCHEMBL27217472 0.75 ESR1 (0.35) ALDH1A1MAPTHSD17B10L3MBTL1HPGD
SCHEMBL21723952 0.73 GSK3B (0.41) ALDH1A1MAPTHSD17B10L3MBTL1HPGD
SCHEMBL23452121 0.73 MAPT (0.37) ALDH1A1MAPTHSD17B10L3MBTL1HPGD
SCHEMBL21723957 0.73 BACE1 (0.39) ALDH1A1MAPTHSD17B10L3MBTL1HPGD
SCHEMBL21723905 0.73 PGR (0.39) ALDH1A1MAPTHSD17B10L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415813-B2 Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KR) 2025-09-16 — — US disclosed
US-20210332063-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) 2021-10-28 — — US disclosed
US-20210332063-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY (KP) 2021-10-28 — — US disclosed
WO-2020036243-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR 한국해양과학기술원 2020-02-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210332063-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR FARS2, CYP4F11, CYP4B1 ALDH1A1 138/4885MAPT 1936/4885HSD17B10 2367/4885
US-12415813-B2 Method for synthesizing thieno[3,2-b]pyridine-5(4H)-one derivative compound, using gold catalyst, and use therefor FARS2, CYP4F11, CYP4B1 ALDH1A1 138/4885MAPT 1936/4885HSD17B10 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.