Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 14/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21726032 | 0.88 | MAOA (0.48) | MAOAMAOBLIMK1CYP19A1CYP11B2 | |
| SCHEMBL21140993 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL21726021 | 0.83 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL21726041 | 0.77 | GABRG2 (0.33) | ALDH1A1GABRG2GABRB3GABRA5 | |
| SCHEMBL18642896 | 0.75 | MAOA (0.47) | MAOAMAOBKDM4ESMN1; SMN2 | |
| SCHEMBL19396447 | 0.73 | MAPK1 (0.35) | KDM4E | |
| SCHEMBL28512593 | 0.73 | MAOA (0.65) | MAOAMAOBLIMK1CYP19A1CYP11B2 | |
| SCHEMBL19764657 | 0.73 | MAOA (0.65) | MAOAMAOBLIMK1CYP19A1CYP11B2 | |
| SCHEMBL14380259 | 0.73 | MAOA (0.65) | MAOAMAOBLIMK1CYP19A1CYP11B2 | |
| SCHEMBL19175545 | 0.71 | CDC25B (0.39) | MAOAKDM4EALDH1A1IDO1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10566547-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10566547-B2 | Organic electroluminescent materials and devices | PAX2, EYA2, NLRP1 | MAOA 2581/4885MAOB 3221/4885LIMK1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.