Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651065 | 0.87 | KMT2A (0.44) | LMNAKDM4ECUL4AMAPTMEN1 | |
| SCHEMBL5630201 | 0.81 | CYP3A4 (0.47) | LMNAKDM4ECYP3A4ACHECUL4A | |
| SCHEMBL5263668 | 0.81 | ACHE (0.54) | LMNAKDM4ECYP3A4ACHECUL4A | |
| SCHEMBL21780744 | 0.81 | NPC1 (0.47) | KDM4EMAPTPOLBGLAGAA | |
| SCHEMBL28068682 | 0.80 | MRGPRX4 (0.48) | LMNAKDM4ECYP3A4ACHECUL4A | |
| SCHEMBL28397412 | 0.80 | LMNA (0.43) | LMNAKDM4ECYP3A4ACHECUL4A | |
| SCHEMBL24716092 | 0.80 | CYP3A4 (0.38) | LMNAKDM4ECYP3A4ACHECUL4A | |
| SCHEMBL22043140 | 0.79 | CYP3A4 (0.40) | LMNAKDM4ECYP3A4ACHECUL4A | |
| SCHEMBL15955653 | 0.78 | KDM4E (0.47) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL27935121 | 0.78 | KDM4E (0.56) | LMNAKDM4ECYP3A4ACHECUL4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611166-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |