Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | S100B | P04271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729526 | 0.79 | TSHR (0.34) | SLC6A2SLC6A4CYP3A4TSHRMAPK1 | |
| SCHEMBL27470244 | 0.76 | CYP3A4 (0.44) | CYP3A4TSHRMAPK1ALDH1A1S100B | |
| SCHEMBL24697160 | 0.72 | IKBKE (0.30) | CYP3A4TSHRMAPK1 | |
| SCHEMBL937859 | 0.72 | KEAP1 (0.50) | CYP3A4ALDH1A1 | |
| SCHEMBL20156578 | 0.72 | CYP3A4 (0.44) | CYP3A4TSHRMAPK1ALDH1A1S100B | |
| SCHEMBL23813891 | 0.71 | ALDH1A1 (0.41) | CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL14404043 | 0.70 | ALOX15 (0.45) | CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL23590577 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL23547681 | 0.70 | ALDH1A1 (0.33) | CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL21587440 | 0.69 | LMNA (0.35) | MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035466-A1 | NOVEL SULFONEUREA COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-02-20 | — | — | WO | disclosed |