Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171351 | 0.90 | LMNA (0.52) | HTR6ALOX12GHSRLMNAHTT | |
| SCHEMBL2171321 | 0.89 | MEN1 (0.46) | HTR6ALOX12LMNAHTTSMN1; SMN2 | |
| SCHEMBL2171141 | 0.86 | HTR6 (0.49) | HTR6GHSRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2170403 | 0.86 | HTR6 (0.50) | HTR6LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL2170726 | 0.85 | HTR6 (0.49) | HTR6CA12CA9LMNAHTT | |
| SCHEMBL2170067 | 0.85 | CCNT1 (0.50) | HTR6LMNAHTTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL2169494 | 0.84 | CCNT1 (0.49) | HTR6LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL2231550 | 0.81 | PPARG (0.49) | HTR6LMNAHTTSMN1; SMN2 | |
| SCHEMBL2171757 | 0.79 | ESR1 (0.47) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL2169949 | 0.79 | ALDH1A1 (0.58) | HTR6LMNAHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | claimed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | claimed |