Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HTR6 | P50406 | 8/20 | 0.52 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | IL1RN | P18510 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171618 | 0.91 | FFAR1 (0.50) | ALDH1A1HTR6LIMK2GAALMNA | |
| SCHEMBL2170713 | 0.90 | L3MBTL1 (0.49) | ALDH1A1HTR6LIMK2LMNAL3MBTL1 | |
| SCHEMBL2169818 | 0.90 | HSD17B2 (0.49) | ALDH1A1HTR6LIMK2GAALMNA | |
| SCHEMBL2171076 | 0.88 | SLC2A1 (0.46) | ALDH1A1HTR6LIMK2LMNAHTT | |
| SCHEMBL2169880 | 0.84 | HTR6 (0.41) | ALDH1A1HTR6LIMK2LMNAMEN1 | |
| SCHEMBL2170403 | 0.81 | HTR6 (0.50) | ALDH1A1HTR6LIMK2GAAHPGD | |
| SCHEMBL2170726 | 0.81 | HTR6 (0.49) | ALDH1A1HTR6LIMK2GAAHPGD | |
| SCHEMBL2170067 | 0.81 | CCNT1 (0.50) | ALDH1A1HTR6LIMK2GAAHPGD | |
| Hydrochloric Acid SCHEMBL2169494 | 0.80 | CCNT1 (0.49) | ALDH1A1HTR6LIMK2GAAHPGD | |
| SCHEMBL2550898 | 0.79 | DDB1 (0.36) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | disclosed |