Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735167 | 0.91 | MTNR1A (0.40) | MCL1MTNR1AMTNR1BTRPV4ALDH1A1 | |
| SCHEMBL21735488 | 0.86 | MTNR1A (0.32) | MCL1MTNR1AMTNR1BAHRTRPV4 | |
| SCHEMBL21735143 | 0.85 | MTNR1A (0.32) | MCL1MTNR1AMTNR1BAHRTRPV4 | |
| SCHEMBL26292555 | 0.83 | MTNR1A (0.44) | MCL1MTNR1AMTNR1BMEN1ALDH1A1 | |
| SCHEMBL21735163 | 0.82 | POLB (0.34) | KCNA5AHRKDM4EMEN1ALDH1A1 | |
| SCHEMBL21735704 | 0.81 | MTNR1A (0.43) | MCL1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL21735152 | 0.79 | CYP11B1 (0.33) | MTNR1AMTNR1BAHRTRPV4CYP11B1 | |
| SCHEMBL22628866 | 0.78 | KCNA5 (0.34) | KCNA5NTRK1KDM4EMEN1ALDH1A1 | |
| SCHEMBL26291812 | 0.78 | MTNR1A (0.45) | MCL1MTNR1AMTNR1BMEN1ALDH1A1 | |
| SCHEMBL21735691 | 0.78 | THRB (0.41) | MCL1MTNR1AMTNR1BKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | KCNA5 355/4885MCL1 3909/4885MTNR1A 3327/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | KCNA5 355/4885MCL1 3909/4885MTNR1A 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.