Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 8/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 8/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 8/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 8/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 8/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735167 | 0.90 | MTNR1A (0.40) | MTNR1AMTNR1BPSEN1PSEN2APH1B | |
| SCHEMBL22628847 | 0.90 | MTNR1A (0.42) | MTNR1AMTNR1BPSEN1PSEN2APH1B | |
| SCHEMBL21735703 | 0.90 | MTNR1A (0.46) | MTNR1AMTNR1BPSEN1PSEN2APH1B | |
| SCHEMBL21735691 | 0.88 | THRB (0.41) | MTNR1AMTNR1BTHRBMCL1HPGD | |
| SCHEMBL21735554 | 0.86 | MTNR1A (0.44) | MTNR1AMTNR1BPSEN1PSEN2APH1B | |
| SCHEMBL26292560 | 0.82 | MTNR1A (0.46) | MTNR1AMTNR1BTHRBMCL1HPGD | |
| SCHEMBL21735162 | 0.81 | KCNA5 (0.33) | MTNR1AMTNR1BMCL1ALDH1A1 | |
| SCHEMBL26292555 | 0.81 | MTNR1A (0.44) | MTNR1AMTNR1BTHRBMCL1ALDH1A1 | |
| SCHEMBL21735547 | 0.80 | NR1H2 (0.45) | THRBHPGDTSHR | |
| SCHEMBL21735853 | 0.79 | MTNR1A (0.42) | MTNR1AMTNR1BMCL1BACE1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | MTNR1A 3327/4885MTNR1B 2622/4885PSEN1 1388/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | MTNR1A 3327/4885MTNR1B 2622/4885PSEN1 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.