Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735204 | 0.88 | PTPN1 (0.46) | PTPN1NCEH1ALDH1A1MAOBMAOA | |
| SCHEMBL21735200 | 0.83 | ALOX5 (0.35) | PTPN1ALDH1A1L3MBTL1 | |
| SCHEMBL21735221 | 0.81 | ALDH1A1 (0.39) | PTPN1NCEH1ALDH1A1L3MBTL1MAOB | |
| SCHEMBL21735193 | 0.78 | MAOB (0.47) | NCEH1ALDH1A1MAOBMAOA | |
| SCHEMBL21735257 | 0.76 | PTPN1 (0.56) | PTPN1ALDH1A1MAOB | |
| SCHEMBL23395607 | 0.71 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAOBMAOA | |
| SCHEMBL21735207 | 0.70 | ALOX5 (0.45) | PTPN1MAOBMAOA | |
| SCHEMBL21735218 | 0.70 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAOBMAOA | |
| SCHEMBL5750613 | 0.70 | NCEH1 (0.57) | NCEH1ALDH1A1L3MBTL1 | |
| SCHEMBL23395580 | 0.67 | PTPN1 (0.62) | PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | PTPN1 4838/4885NCEH1 508/4885ALDH1A1 1851/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | PTPN1 4838/4885NCEH1 508/4885ALDH1A1 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.