Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735207 | 0.89 | ALOX5 (0.45) | ALOX5S1PR1PPARGPPARAPTGES | |
| SCHEMBL22629183 | 0.85 | ALOX5 (0.37) | ALOX5S1PR1PPARGPPARAALDH1A1 | |
| SCHEMBL21735203 | 0.85 | ALDH1A1 (0.35) | ALOX5S1PR1PPARAALDH1A1S1PR3 | |
| SCHEMBL22628800 | 0.84 | ALOX5 (0.35) | ALOX5S1PR1PPARGPPARAALDH1A1 | |
| SCHEMBL21735279 | 0.83 | PTPN1 (0.34) | ALDH1A1L3MBTL1PTPN1 | |
| SCHEMBL21735356 | 0.81 | ALOX5 (0.49) | ALOX5ALDH1A1PTGESALOX15PTPN1 | |
| SCHEMBL26291493 | 0.81 | THRB (0.38) | ALOX5S1PR1PPARGPPARAALDH1A1 | |
| SCHEMBL26291496 | 0.81 | ALOX5 (0.33) | ALOX5S1PR1PPARGPPARAALDH1A1 | |
| SCHEMBL20473343 | 0.80 | ALOX5 (0.38) | ALOX5S1PR1PPARGPPARAALDH1A1 | |
| SCHEMBL21735540 | 0.79 | PTPN1 (0.49) | ALOX5S1PR1PPARGPPARAS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | ALOX5 167/4885S1PR1 3951/4885PPARG 749/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | ALOX5 167/4885S1PR1 3951/4885PPARG 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.