Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192436 | 0.86 | CHRM2 (0.53) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL12802773 | 0.85 | LMNA (0.49) | MMP2MMP9CHRM2MEN1CYP1A2 | |
| SCHEMBL2176242 | 0.84 | MMP2 (0.46) | MMP2MMP9CHRM2MMP3MMP13 | |
| SCHEMBL12802824 | 0.76 | MMP2 (0.41) | MMP2MMP9CHRM2MMP3MMP13 | |
| SCHEMBL12482645 | 0.76 | ALDH1A1 (0.56) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL4908730 | 0.75 | LMNA (0.44) | MMP2MMP9MMP13MEN1CYP2C19 | |
| Bromide SCHEMBL10915166 | 0.74 | LMNA (0.43) | MMP2MMP9MMP13MEN1CYP2C19 | |
| SCHEMBL9504553 | 0.74 | CHRM2 (0.66) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL12484122 | 0.72 | CASP3 (0.50) | CHRM2MEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL10428952 | 0.72 | CYP3A4 (0.60) | KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512409-B1 | PHTHALIMIDES AS BLEACH ACTIVATORS | HENKEL AG & CO KGAA (DE) | 2014-12-17 | — | — | EP | claimed |
| US-8328879-B2 | Phthalimides as bleach activators | HENKEL AG & CO. KGAA (DE) | 2012-12-11 | — | — | US | claimed |
| EP-2512409-A2 | PHTALIMIDES AS BLEACH ACTIVATORS | Henkel AG & Co. KGaA (DE) | 2012-10-24 | — | — | EP | claimed |
| US-20120246841-A1 | PHTHALIMIDES AS BLEACH ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2012-10-04 | — | — | US | claimed |
| WO-2011079974-A2 | PHTALIMIDES AS BLEACH ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2011-07-07 | — | — | WO | claimed |
| EP-2512409-B1 | PHTHALIMIDES AS BLEACH ACTIVATORS | HENKEL AG & CO KGAA (DE) | 2014-12-17 | — | — | EP | disclosed |
| US-8328879-B2 | Phthalimides as bleach activators | HENKEL AG & CO. KGAA (DE) | 2012-12-11 | — | — | US | disclosed |
| EP-2512409-A2 | PHTALIMIDES AS BLEACH ACTIVATORS | Henkel AG & Co. KGaA (DE) | 2012-10-24 | — | — | EP | disclosed |
| US-20120246841-A1 | PHTHALIMIDES AS BLEACH ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2012-10-04 | — | — | US | disclosed |
| WO-2011079974-A2 | PHTALIMIDES AS BLEACH ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120246841-A1 | PHTHALIMIDES AS BLEACH ACTIVATORS | KRT18, PPOX, CRYAA | CHRM2 4093/4885MMP2 653/4885MMP9 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.