SCHEMBL2174158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL265128	1.00	ALDH1A1 (0.50)	ALDH1A1MEN1KMT2AHPGDTDP1
	SCHEMBL1353556	0.98	MEN1 (0.52)	ALDH1A1MEN1KMT2AHPGDTDP1
	SCHEMBL1699410	0.94	DHFR (0.50)	ALDH1A1MEN1KMT2AHPGDTDP1
	SCHEMBL22685038	0.84	ALDH1A1 (0.59)	ALDH1A1MEN1KMT2AHPGDTDP1
	SCHEMBL28820505	0.82	HTR7 (0.50)	ALDH1A1MEN1KMT2AHPGDGAA
	SCHEMBL2190020	0.82	MEN1 (0.52)	ALDH1A1MEN1KMT2ADHFRALOX5
	Bromobenzene SCHEMBL28019698	0.81	L3MBTL1 (0.50)	ALDH1A1MEN1KMT2AHPGDTDP1
	SCHEMBL689422	0.80	HTR7 (0.62)	ALDH1A1MAPTHTT
	SCHEMBL1559226	0.80	ADRA2C (0.65)	ALDH1A1MEN1KMT2AGAAKDM4E
	SCHEMBL4750843	0.80	DHFR (0.50)	ALDH1A1MEN1KMT2ASMN1; SMN2DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.