Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.62 |
| ▸ | HTR1A | P08908 | 6/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.62 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.62 |
| ▸ | HTR3B | O95264 | 4/20 | 0.62 |
| ▸ | HTR3A | P46098 | 4/20 | 0.62 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.62 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.62 |
| ▸ | HTR2C | P28335 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4661519 | 0.98 | HTR7 (0.61) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL28079384 | 0.89 | HTR7 (0.50) | HTR7HTR1AADRB1HTR3EHTR3B | |
| Tert-Butyl Formate SCHEMBL27824904 | 0.83 | ADRB1 (0.50) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL1699410 | 0.82 | DHFR (0.50) | ALDH1A1 | |
| SCHEMBL1353556 | 0.82 | MEN1 (0.52) | HTTALDH1A1MAPT | |
| Tert-Butyl Formate SCHEMBL28119361 | 0.82 | ADRB1 (0.49) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL17276711 | 0.80 | ADRB1 (0.67) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL2174158 | 0.80 | ALDH1A1 (0.50) | HTTALDH1A1MAPT | |
| SCHEMBL265128 | 0.80 | ALDH1A1 (0.50) | HTTALDH1A1MAPT | |
| SCHEMBL30087959 | 0.79 | CHRNB2 (0.47) | HTR7HTR1AADRB1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017659-A | Benzimidazole and thiazole carboxamides class compound and its application | 沈阳药科大学 | 2018-05-11 | — | — | CN | claimed |
| US-20260109708-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS DEGRADERS OF MK2 KINASE | CELGENE CORP (US) | 2026-04-23 | — | — | US | disclosed |
| US-20250388584-A1 | TPK AGONIST AND METHOD FOR TREATING NEURODEGENERATIVE DISEASES USING SAME | SHANGHAI RAISING PHARMACEUTICAL CO LTD (CN) | 2025-12-25 | — | — | US | disclosed |
| EP-4661875-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS DEGRADERS OF MK2 KINASE | Celgene Corporation (US) | 2025-12-17 | — | — | EP | disclosed |
| EP-4556007-A1 | TPK AGONIST AND METHOD FOR TREATING NEURODEGENERATIVE DISEASES USING SAME | Shanghai Raising Pharmaceutical Co., Ltd. (CN) | 2025-05-21 | — | — | EP | disclosed |
| CN-119497615-A | TPK agonists and methods of using the same for treating neurodegenerative diseases | 上海日馨医药科技股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| US-20250026749-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2025-01-23 | — | — | US | disclosed |
| WO-2024260023-A1 | CYCLIC Α-HYDROXYIMIDE COMPOUND AND USE THEREOF | 北京英飞智药科技有限公司 | 2024-12-26 | — | — | WO | disclosed |
| CN-116444461-B | Dibenzylbutane lignan LCA derivative and application thereof | 中国人民解放军海军军医大学 | 2024-12-24 | — | — | CN | disclosed |
| CN-119176777-A | Cyclic alpha-hydroxyimide compound and application thereof | 北京英飞智药科技有限公司 | 2024-12-24 | — | — | CN | disclosed |
| US-5627196-A | ANTIDEPRESSANTS AND ANTISEROTONIN AGENTS | ELI LILLY AND COMPANY (US) | 1997-05-06 | — | — | US | disclosed |
| US-5614523-A | INDOLYLOXY COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| US-5576321-A | ALKOXY-SUBSTITUTED INDOLES | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| WO-1996022290-A1 | COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| EP-0722941-A2 | Compounds having effects on serotonin-related systems | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |
| EP-0015615-B1 | PHENYL PIPERAZINE DERIVATIVES, THEIR PREPARATION AND ANTIAGRESSIVE MEDICINES CONTAINING THEM | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1983-01-12 | — | — | EP | disclosed |
| EP-0015615-A1 | Phenyl piperazine derivatives, their preparation and antiagressive medicines containing them | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1980-09-17 | — | — | EP | disclosed |
| US-4123529-A | TREATMENT OF ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1978-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250026749-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GBA1, GBA2, GAA | HTR7 4826/4885HTR1A 4709/4885ADRB1 4481/4885 |
| US-20260109708-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS DEGRADERS OF MK2 KINASE | PSME2, MKRN3, RPS6KA2 | HTR7 3543/4885HTR1A 3795/4885ADRB1 1800/4885 |
| US-20250388584-A1 | TPK AGONIST AND METHOD FOR TREATING NEURODEGENERATIVE DISEASES USING SAME | PDXK, SLC19A2, NADK | HTR7 418/4885HTR1A 469/4885ADRB1 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.