Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.54 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072231 | 0.87 | ADRA1D (0.58) | ALDH1A1SIGMAR1DRD4MCHR1MEN1 | |
| SCHEMBL21774707 | 0.81 | USP14 (0.63) | ALDH1A1SSTR1SSTR4DRD2MEN1 | |
| SCHEMBL3590338 | 0.81 | SIGMAR1 (0.73) | ALDH1A1SIGMAR1DRD4TEAD1MCHR1 | |
| SCHEMBL15340905 | 0.80 | KMT2A (0.64) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21748552 | 0.80 | KMT2A (0.51) | ALDH1A1DRD2MEN1KMT2A | |
| SCHEMBL3587801 | 0.78 | SIGMAR1 (0.61) | SIGMAR1DRD4DRD2TEAD1CCR2 | |
| SCHEMBL4874296 | 0.77 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2A | |
| SCHEMBL26921192 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2A | |
| SCHEMBL22716940 | 0.76 | DRD2 (0.66) | SIGMAR1DRD4DRD2TEAD1CCR2 | |
| SCHEMBL3586870 | 0.76 | SIGMAR1 (0.55) | SIGMAR1DRD4TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12005054-B2 | Piperidinyl-3-(aryloxy)propanamides and propanoates | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-06-11 | — | — | US | disclosed |
| US-20230021834-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-01-26 | — | — | US | disclosed |
| US-11045457-B2 | Piperidinyl-3-(aryloxy)propanamides and propanoates | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20200061041-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11045457-B2 | Piperidinyl-3-(aryloxy)propanamides and propanoates | SSTR4, SSTR3, NPY4R | ALDH1A1 1476/4885SSTR1 4/4885SSTR4 1/4885 |
| US-12005054-B2 | Piperidinyl-3-(aryloxy)propanamides and propanoates | SSTR4, SSTR3, NPY4R | ALDH1A1 1476/4885SSTR1 4/4885SSTR4 1/4885 |
| US-20200061041-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | SSTR4, SSTR3, NPY4R | ALDH1A1 1476/4885SSTR1 4/4885SSTR4 1/4885 |
| US-20230021834-A1 | PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES | SSTR4, SSTR3, NPY4R | ALDH1A1 1476/4885SSTR1 4/4885SSTR4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.