SCHEMBL21753775

SCHEMBL21753775

CCc1ccc2c(c1)-c1ccccc1[N]2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
ALDH1A1 P00352 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
NPC1 O15118 1/20 0.52
LMNA P02545 1/20 0.52
MAPK1 P28482 1/20 0.52
RAB9A P51151 1/20 0.52
CYP1A2 P05177 2/20 0.44
CYP2A6 P11509 1/20 0.44
PDK2 Q15119 1/20 0.38
TP53 P04637 1/20 0.38
KIF11 P52732 1/20 0.37
TRPA1 O75762 1/20 0.36
PLA2G1B P04054 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18917479 0.90 SMN1; SMN2 (0.45) MAPTSMN1; SMN2ALDH1A1L3MBTL1NPC1
SCHEMBL3868812 0.82 PSMB5 (0.47) ALDH1A1NPC1MAPK1RAB9AHPGD
SCHEMBL27620561 0.81 PDK2 (0.39) MAPTSMN1; SMN2ALDH1A1L3MBTL1NPC1
SCHEMBL3869128 0.80 GPR3 (0.52) ALDH1A1LMNATP53KDM4ECYP3A4
SCHEMBL3868634 0.80 GPR3 (0.52) ALDH1A1LMNATP53KDM4ECYP3A4
SCHEMBL3879614 0.80 GPR3 (0.52) ALDH1A1LMNATP53KDM4ECYP3A4
SCHEMBL23537714 0.77 SMN1; SMN2 (0.45) MAPTSMN1; SMN2ALDH1A1L3MBTL1NPC1
SCHEMBL20553770 0.76 LTA4H (0.56) MAPTSMN1; SMN2ALDH1A1L3MBTL1NPC1
SCHEMBL20553960 0.74 LTA4H (0.46) GAA
SCHEMBL20553740 0.74 HTR7 (0.46) LMNACYP1A2TP53CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11937495-B2 Organic light emitting element, composition and membrane KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-03-19 US disclosed
EP-3843168-B1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE UNIV KYUSHU NAT UNIV CORP (JP) 2023-10-11 EP disclosed
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT KYULUX, INC. (JP) 2021-07-01 US disclosed
US-20210202851-A1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE KYULUX, INC. (JP) 2021-07-01 US disclosed
EP-3843167-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Kyushu University, National University Corporation (JP) 2021-06-30 EP disclosed
EP-3843168-A1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE Kyushu University, National University Corporation (JP) 2021-06-30 EP disclosed
CN-112602206-A Organic electroluminescent element 国立大学法人九州大学 2021-04-02 CN disclosed
CN-112585778-A Organic light-emitting element, composition, and film 国立大学法人九州大学 2021-03-30 CN disclosed
WO-2020039708-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT 国立大学法人九州大学 2020-02-27 WO disclosed
WO-2020039930-A1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE 国立大学法人九州大学 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11937495-B2 Organic light emitting element, composition and membrane CRY1, INTS9, CYBA MAPT 3556/4885SMN1; SMN2 3937/4885ALDH1A1 1140/4885
US-20210202851-A1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE CRY1, INTS9, CYBA MAPT 3556/4885SMN1; SMN2 3937/4885ALDH1A1 1140/4885
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, EMC1, EEA1 MAPT 2405/4885SMN1; SMN2 2052/4885ALDH1A1 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.