Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.58 |
| ▸ | DRD3 | P35462 | 14/20 | 0.58 |
| ▸ | DRD4 | P21917 | 8/20 | 0.58 |
| ▸ | HTR2A | P28223 | 6/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | DRD1 | P21728 | 3/20 | 0.48 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911015 | 0.79 | DRD2 (0.76) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL1513400 | 0.71 | DRD2 (0.62) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL6619068 | 0.69 | CXCR6 (0.48) | DRD2DRD3SIGMAR1 | |
| SCHEMBL2448427 | 0.68 | DRD2 (0.62) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL30608313 | 0.68 | DRD2 (0.62) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL1206358 | 0.68 | DRD2 (0.78) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL707808 | 0.68 | CHRM2 (0.53) | SIGMAR1 | |
| SCHEMBL719296 | 0.68 | CHRM2 (0.53) | SIGMAR1 | |
| SCHEMBL29691892 | 0.68 | CHRM2 (0.53) | SIGMAR1 | |
| SCHEMBL19364501 | 0.68 | CHRM2 (0.53) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062768-A1 | CX3CR1 Small Molecule Antagonists, and Methods Using Same | DREXEL UNIVERSITY | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062768-A1 | CX3CR1 Small Molecule Antagonists, and Methods Using Same | CX3CR1, CCR5, CXCR3 | DRD2 831/4885DRD3 1200/4885DRD4 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.