SCHEMBL21756068

SCHEMBL21756068

Cc1ccc(-c2ccc(F)cc2F)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
NPC1 O15118 2/20 0.46
ALOX15 P16050 2/20 0.46
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
THRB P10828 1/20 0.45
CA3 P07451 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
DHFR P00374 1/20 0.44
CA1 P00915 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13674310 0.87 NFE2L2 (0.50) MEN1KMT2AALDH1A1HPGDTHRB
SCHEMBL12627935 0.82 MEN1 (0.46) MEN1KMT2AALDH1A1HPGDTHRB
SCHEMBL30069362 0.82 MEN1 (0.46) MEN1KMT2AALDH1A1HPGDTHRB
SCHEMBL21756067 0.81 TRPA1 (0.43) TRPA1MEN1KMT2ANPC1ALOX15
SCHEMBL29819939 0.80 TRPA1 (0.68) TRPA1MEN1KMT2ANPC1ALOX15
SCHEMBL340066 0.80 TRPA1 (0.68) TRPA1MEN1KMT2ANPC1ALOX15
SCHEMBL13520606 0.78 GRM2 (0.44) TRPA1MEN1KMT2AALOX15ALDH1A1
SCHEMBL21021957 0.78 TRPA1 (0.48) TRPA1MEN1KMT2ANPC1ALOX15
SCHEMBL16429428 0.78 CA3 (0.46) MEN1KMT2ANPC1ALOX15RAB9A
SCHEMBL9135463 0.78 ALDH1A1 (0.52) MEN1KMT2AALDH1A1HPGDCA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020040571-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-27 WO disclosed