SCHEMBL21756067

SCHEMBL21756067

Cc1ccc(-c2ccc(Br)cc2F)c(O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.43
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NMUR2 Q9GZQ4 1/20 0.39
CSNK2A2 P19784 1/20 0.39
CSNK2B P67870 1/20 0.39
CSNK2A1 P68400 1/20 0.39
BCL2 P10415 1/20 0.39
MCL1 Q07820 1/20 0.39
ALDH1A1 P00352 2/20 0.38
ALOX15 P16050 2/20 0.38
DGAT1 O75907 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ALOX5 P09917 3/20 0.38
TP53 P04637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPK1 P28482 1/20 0.38
PTGES O14684 1/20 0.38
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27164738 0.86 BCL2 (0.45) MEN1KMT2ANMUR2BCL2MCL1
SCHEMBL21756068 0.81 TRPA1 (0.46) TRPA1MEN1KMT2AALDH1A1ALOX15
SCHEMBL31310573 0.79 DGAT1 (0.46) NMUR2BCL2MCL1ALDH1A1ALOX15
SCHEMBL14520998 0.79 DGAT1 (0.46) NMUR2BCL2MCL1ALDH1A1ALOX15
SCHEMBL1357074 0.79 HPGD (0.47) MEN1KMT2ANMUR2BCL2MCL1
SCHEMBL21651117 0.78 LMNA (0.43) MEN1KMT2ANMUR2BCL2MCL1
SCHEMBL23253866 0.77 AMY1A (0.42) TRPA1MEN1KMT2AALDH1A1DGAT1
SCHEMBL21756115 0.77 ACHE (0.46) ALDH1A1NPC1RAB9ATDP1
SCHEMBL9223676 0.77 ALOX5AP (0.46) MEN1KMT2AALDH1A1DGAT1NPC1
SCHEMBL340066 0.77 TRPA1 (0.68) TRPA1MEN1KMT2ACSNK2A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020040571-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-27 WO disclosed