Sugi Predict

Sugi Predict / Compounds / SCHEMBL2175643

SCHEMBL2175643

SCHEMBL2175643

CC(C)(O)c1ccc(CO)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 1/20 0.46
▸ PPARG P37231 1/20 0.42
▸ PPARA Q07869 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ ESR1 P03372 3/20 0.40
▸ ESR2 Q92731 2/20 0.40
▸ KIF11 P52732 1/20 0.39
▸ NOS3 P29474 1/20 0.39
▸ NOS1 P29475 1/20 0.39
▸ PRSS1 P07477 1/20 0.38
▸ PRSS2 P07478 1/20 0.38
▸ PRSS3 P35030 1/20 0.38
▸ KLF10 Q13118 1/20 0.38
▸ VHL P40337 1/20 0.37
▸ ELOC Q15369 1/20 0.37
▸ ELOB Q15370 1/20 0.37
▸ LTA4H P09960 1/20 0.37
▸ CA12 O43570 1/20 0.37
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzyl Alcohol SCHEMBL28034493 0.84 TSHR (0.61) PPARGPPARATSHRESR1ESR2
SCHEMBL113722 0.82 EPHX2 (0.61) EPHX2PPARGPPARATSHR
SCHEMBL787308 0.82 ESR1 (0.52) EPHX2PPARGPPARATSHRESR1
SCHEMBL128572 0.82 LPL (0.46) ESR1ESR2KIF11MEN1KMT2A
SCHEMBL548192 0.82 MEN1 (0.45) ESR1ESR2MEN1KMT2ACCR9
SCHEMBL548475 0.82 ESR1 (0.43) TSHRESR1ESR2MEN1KMT2A
SCHEMBL23355560 0.81 CA2 (0.50) PPARATSHRESR1ESR2CA12
SCHEMBL196799 0.81 MEN1 (0.48) TSHRESR1ESR2TNKSPARP1
SCHEMBL22222995 0.79 ESR1 (0.44) EPHX2PPARGPPARATSHRESR1
SCHEMBL14012098 0.78 PDE2A (0.45) EPHX2PPARGPPARATSHRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023020398-A1 POLYCARBONATE/POLYESTER ALLOY COMPOSITION HAVING LONG-TERM THERMAL OXYGEN STABILITY, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 金发科技股份有限公司 2023-02-23 — — WO claimed
US-20250170283-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-29 — — US disclosed
CN-113754589-B Compositions, methods, and systems for synthesizing and using contrast agents 蓝瑟斯医学影像公司 2024-09-27 — — CN disclosed
US-20240100199-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2024-03-28 — — US disclosed
US-20240092774-A1 HETEROAROMATIC COMPOUNDS AND USES THEREOF HUTCHISON MEDIPHARMA LIMITED (CN) 2024-03-21 — — US disclosed
US-20240076297-A1 ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY MERCK SHARP & DOHME LLC (US) 2024-03-07 — — US disclosed
US-11744906-B2 Compositions, methods, and systems for the synthesis and use of imaging agents LANTHEUS MEDICAL IMAGING, INC. (US) 2023-09-05 — — US disclosed
EP-4214198-A1 HETEROAROMATIC COMPOUNDS AND USES THEREOF Hutchison Medipharma Limited (CN) 2023-07-26 — — EP disclosed
CN-116323582-A Heteroaromatic ring compounds and uses thereof 和记黄埔医药（上海）有限公司 2023-06-23 — — CN disclosed
EP-4185297-A1 ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY Merck Sharp & Dohme LLC (US) 2023-05-31 — — EP disclosed
EP-2278969-B1 Inhibitors of Janus kinases MERCK SHARP & DOHME (US) 2013-02-13 — — EP disclosed
US-8278335-B2 Inhibitors of Janus kinases MERCK SHARP & DOHME CORP. (US) 2012-10-02 — — US disclosed
US-8278335-B2 Inhibitors of Janus kinases MERCK SHARP & DOHME CORP. (US) 2012-10-02 — — US disclosed
US-8278335-B2 Inhibitors of Janus kinases MERCK SHARP & DOHME CORP. (US) 2012-10-02 — — US disclosed
US-20110166129-A1 INHIBITORS OF JANUS KINASES MERCK SHARP & DOHME LLC 2011-07-07 — — US disclosed
US-20110166129-A1 INHIBITORS OF JANUS KINASES MERCK SHARP & DOHME LLC 2011-07-07 — — US disclosed
US-20110166129-A1 INHIBITORS OF JANUS KINASES MERCK SHARP & DOHME LLC 2011-07-07 — — US disclosed
WO-2010011375-A2 INHIBITORS OF JANUS KINASES MERCK & CO., INC. (US) 2010-01-28 — — WO disclosed
US-5280096-A Optically active polymer UNIVERSITY OF NEW MEXICO (US) 1994-01-18 — — US disclosed
US-5166062-A Reaction a mixture of acyl esters with enzymes and selectively deacylating followed by separation UNIVERSITY OF NEW MEXICO (US) 1992-11-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170283-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 EPHX2 168/4885PPARG 2230/4885PPARA 2493/4885
US-20240076297-A1 ADENOSINE A2A AND A2B RECEPTOR DUAL ANTAGONISTS FOR IMMUNO-ONCOLOGY ADORA2A, ADORA2B, ADORA1 EPHX2 509/4885PPARG 1101/4885PPARA 935/4885
US-20240092774-A1 HETEROAROMATIC COMPOUNDS AND USES THEREOF CYP2D6, CYP3A7, CYP2F1 EPHX2 111/4885PPARG 607/4885PPARA 930/4885
US-20110166129-A1 INHIBITORS OF JANUS KINASES JAK2, JAK3, JAK1 EPHX2 4752/4885PPARG 1900/4885PPARA 2220/4885
US-20240100199-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 EPHX2 168/4885PPARG 2230/4885PPARA 2493/4885
US-11744906-B2 Compositions, methods, and systems for the synthesis and use of imaging agents FABP3, TNNI3, TNNT2 EPHX2 168/4885PPARG 2230/4885PPARA 2493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.