Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28011820 | 0.90 | BMP1 (0.48) | BMP1MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL2177818 | 0.90 | BMP1 (0.48) | BMP1MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL19051462 | 0.87 | BMP1 (0.54) | BMP1HTTPOLB | |
| SCHEMBL11338769 | 0.82 | MAPK1 (0.46) | ALDH1A1MAPK1 | |
| SCHEMBL6130220 | 0.81 | HDAC6 (0.39) | KMT2AL3MBTL1MAPTALDH1A1TP53 | |
| SCHEMBL9828822 | 0.80 | MAPK1 (0.45) | ALDH1A1MAPK1 | |
| SCHEMBL9828841 | 0.80 | MAPK1 (0.45) | ALDH1A1MAPK1 | |
| SCHEMBL7030418 | 0.80 | CTSL (0.50) | TYR | |
| SCHEMBL29401219 | 0.80 | ALDH1A1 (0.54) | MEN1KMT2AMAPTALDH1A1TRPM8 | |
| Water SCHEMBL11367778 | 0.79 | MAPK1 (0.44) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623900-B2 | Amino alcohol derivatives and their therapeutic activities | FLAMMA S.P.A. (IT) | 2014-01-07 | — | — | US | disclosed |
| EP-2519507-B1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | FLAMMA SPA (IT) | 2013-10-16 | — | — | EP | disclosed |
| US-20120316212-A1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2012-12-13 | — | — | US | disclosed |
| EP-2519507-A1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | Flamma S.P.A. (IT) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080139-A1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | FLAMMA S.P.A. (IT) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316212-A1 | AMINO ALCOHOL DERIVATIVES AND THEIR THERAPEUTIC ACTIVITIES | ADH1A, ADH5, ADH1C | BMP1 4746/4885MEN1 4864/4885KMT2A 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.