Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.43 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769498 | 0.92 | HSD17B10 (0.40) | ALDH1A1KDM4EHSP90B1TRAP1MAPT | |
| SCHEMBL21769483 | 0.89 | TRAP1 (0.43) | ALDH1A1KDM4EHSP90B1TRAP1MAPT | |
| SCHEMBL21769536 | 0.84 | NPC1 (0.52) | ALDH1A1MAPTL3MBTL1KCNA5HTT | |
| SCHEMBL21769236 | 0.84 | HSP90B1 (0.44) | ALDH1A1HSP90B1TRAP1MAPTL3MBTL1 | |
| SCHEMBL21769235 | 0.84 | NPSR1 (0.47) | ALDH1A1KDM4EMAPTL3MBTL1NPSR1 | |
| SCHEMBL21769535 | 0.83 | MGLL (0.48) | HSP90B1TRAP1 | |
| SCHEMBL21769476 | 0.83 | MAPT (0.44) | KDM4EMAPTL3MBTL1NPSR1 | |
| SCHEMBL21769237 | 0.83 | CCNK (0.44) | ALDH1A1KDM4EMAPTL3MBTL1NPSR1 | |
| SCHEMBL21440788 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPSR1HTTCACNA1G | |
| SCHEMBL21769473 | 0.81 | NPSR1 (0.48) | ALDH1A1KDM4EMAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11022604-B2 | Dock derived compound against laminin receptor (37 LR) and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | ILK, LRRC47, RPL37 | ALDH1A1 1721/4885KDM4E 3638/4885HSP90B1 437/4885 |
| US-11022604-B2 | Dock derived compound against laminin receptor (37 LR) and uses thereof | ILK, LRRC47, RPL37 | ALDH1A1 1721/4885KDM4E 3638/4885HSP90B1 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.