Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90B1 | P14625 | 2/20 | 0.44 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769483 | 0.95 | TRAP1 (0.43) | HSP90B1TRAP1PDK2MAPTMAPK1 | |
| SCHEMBL21769253 | 0.92 | HSP90B1 (0.40) | HSP90B1TRAP1PDK2ALDH1A1FAAH | |
| SCHEMBL21769244 | 0.85 | NPSR1 (0.48) | MAPTMAPK1NPSR1HTTCACNA1G | |
| SCHEMBL21769538 | 0.84 | CACNA1B (0.53) | ALDH1A1 | |
| SCHEMBL21769474 | 0.84 | ALDH1A1 (0.43) | HSP90B1TRAP1PDK2MAPTNPSR1 | |
| SCHEMBL21769537 | 0.84 | MGLL (0.48) | HSP90B1TRAP1ALDH1A1FAAHMGLL | |
| SCHEMBL21769398 | 0.82 | KDM4E (0.46) | NPSR1ALDH1A1HTTCACNA1G | |
| SCHEMBL21769232 | 0.81 | THRA (0.44) | HSP90B1TRAP1MAPTMAPK1NPSR1 | |
| SCHEMBL21769473 | 0.80 | NPSR1 (0.48) | MAPTMAPK1NPSR1ALDH1A1HTT | |
| SCHEMBL21769536 | 0.79 | NPC1 (0.52) | MAPTALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11022604-B2 | Dock derived compound against laminin receptor (37 LR) and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | ILK, LRRC47, RPL37 | HSP90B1 437/4885TRAP1 200/4885PDK2 1327/4885 |
| US-11022604-B2 | Dock derived compound against laminin receptor (37 LR) and uses thereof | ILK, LRRC47, RPL37 | HSP90B1 437/4885TRAP1 200/4885PDK2 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.