Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8754909 | 0.76 | HSD11B1 (0.39) | HSD11B1TSHRPSMB5PTPN1GPR84 | |
| SCHEMBL1817005 | 0.69 | PTGS2 (0.46) | PTPN1 | |
| SCHEMBL27876741 | 0.67 | GCGR (0.49) | HSD11B1TSHRPSMB5PTPN1GPR84 | |
| SCHEMBL8755192 | 0.67 | PTPN1 (0.34) | HSD11B1TSHRPTPN1GPR84HTT | |
| Biphenyl SCHEMBL15347228 | 0.66 | ALDH1A1 (0.56) | HSD11B1TSHRGPR84HTTSIGMAR1 | |
| Biphenyl SCHEMBL5868585 | 0.66 | ALDH1A1 (0.56) | HSD11B1TSHRGPR84NR1H3 | |
| Biphenyl SCHEMBL27954388 | 0.66 | LIPG (0.48) | HSD11B1TSHRGPR84NR1H3ADORA3 | |
| SCHEMBL3223722 | 0.65 | ALDH1A1 (0.40) | TSHRACHEHTT | |
| SCHEMBL402463 | 0.65 | HSD11B1 (0.68) | HSD11B1TSHRPSMB5 | |
| SCHEMBL9158283 | 0.65 | HSD11B1 (0.68) | HSD11B1TSHRPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071428-A1 | CATALYST SYSTEM FOR MULTI-BLOCK COPLOYMER FORMATION | DOW GLOBAL TECHNOLOGIES LLC | 2020-03-05 | — | — | US | disclosed |