SCHEMBL21777460

SCHEMBL21777460

CCCCc1cc(CCC(N)=O)cc(CCCC)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.49
CNR1 P21554 1/20 0.41
NPC1 O15118 1/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
KDM4E B2RXH2 2/20 0.40
SOAT1 P35610 2/20 0.40
CYP3A4 P08684 2/20 0.40
IAPP P10997 1/20 0.40
MEN1 O00255 1/20 0.40
FAAH O00519 1/20 0.40
TP53 P04637 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
TLR8 Q9NR97 1/20 0.39
TYR P14679 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8589319 0.86 CAPN1 (0.42) EGFRCYP3A4IAPPMEN1CYP1A2
SCHEMBL4854721 0.85 THRA (0.49) EGFRNPC1HPGDMAPK1HTT
SCHEMBL25307665 0.85 EGFR (0.43) EGFRNPC1HPGDMAPK1HTT
SCHEMBL2230841 0.84 EGFR (0.44) EGFRNPC1HPGDMAPK1HTT
SCHEMBL28002486 0.83 ALDH1A1 (0.44) EGFRNPC1HPGDMAPK1HTT
SCHEMBL27836584 0.83 GAA (0.56) EGFRNPC1HPGDMAPK1HTT
SCHEMBL1629297 0.82 HDAC3 (0.47) EGFRNPC1HPGDMAPK1HTT
SCHEMBL201692 0.82 NPC1 (0.57) EGFRNPC1HPGDMAPK1HTT
SCHEMBL7615859 0.81 ALOX5 (0.43) EGFRNPC1HPGDMAPK1HTT
SCHEMBL18269260 0.81 DGKA (0.47) EGFRALDH1A1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912442-B Copolyetherester formulation with improved thermal stability 杜邦聚合物公司 2023-06-20 CN claimed
EP-3844220-A1 COPOLYETHERESTER FORMULATION WITH IMPROVED HEAT-STABILITY DUPONT POLYMERS, INC. (US) 2021-07-07 EP claimed
CN-112912442-A Copolyether ester formulation with improved thermal stability 杜邦聚合物公司 2021-06-04 CN claimed
WO-2020047406-A1 COPOLYETHERESTER FORMULATION WITH IMPROVED HEAT-STABILITY DUPONT POLYMERS, INC (US) 2020-03-05 WO claimed
CN-112912442-B Copolyetherester formulation with improved thermal stability 杜邦聚合物公司 2023-06-20 CN disclosed
EP-3844220-A1 COPOLYETHERESTER FORMULATION WITH IMPROVED HEAT-STABILITY DUPONT POLYMERS, INC. (US) 2021-07-07 EP disclosed
CN-112912442-A Copolyether ester formulation with improved thermal stability 杜邦聚合物公司 2021-06-04 CN disclosed
WO-2020047406-A1 COPOLYETHERESTER FORMULATION WITH IMPROVED HEAT-STABILITY DUPONT POLYMERS, INC (US) 2020-03-05 WO disclosed
CN-104619776-A Polyamide resin composition and molded article TORAY INDUSTRIES 2015-05-13 CN disclosed