Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21777460 | 0.84 | EGFR (0.49) | EGFRNPC1HPGDMAPK1HTT | |
| SCHEMBL25307665 | 0.82 | EGFR (0.43) | EGFRNPC1HPGDMAPK1HTT | |
| SCHEMBL4854721 | 0.82 | THRA (0.49) | EGFRNPC1HPGDMAPK1HTT | |
| SCHEMBL28002486 | 0.81 | ALDH1A1 (0.44) | EGFRNPC1HPGDMAPK1HTT | |
| SCHEMBL27836584 | 0.80 | GAA (0.56) | EGFRNPC1HPGDMAPK1HTT | |
| SCHEMBL7047486 | 0.80 | CYP4F2 (0.50) | EGFRNPC1HPGDMAPK1HTT | |
| SCHEMBL1629297 | 0.79 | HDAC3 (0.47) | EGFRNPC1HPGDMAPK1HTT | |
| SCHEMBL201692 | 0.79 | NPC1 (0.57) | EGFRNPC1HPGDMAPK1HTT | |
| SCHEMBL18269260 | 0.78 | DGKA (0.47) | EGFRALOX5 | |
| SCHEMBL7615859 | 0.78 | ALOX5 (0.43) | EGFRNPC1HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104194413-A | Pigment preparations | MERCK PATENT GMBH | 2014-12-10 | — | — | CN | disclosed |
| EP-2512397-A1 | PLASTIC PRESSURE VESSEL FOR BIOPHARMACEUTICAL APPLICATIONS AND METHODS THEREOF | 3M Innovative Properties Company (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084176-A1 | PLASTIC PRESSURE VESSEL FOR BIOPHARMACEUTICAL APPLICATIONS AND METHODS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2009033694-A2 | CABLE COMPRISING BEDDING WITH REDUCED AMOUNT OF VOLATILE COMPOUNDS | BOREALIS TECHNOLOGY OY (FI) | 2009-03-19 | — | — | WO | disclosed |