Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IAPP | P10997 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712571 | 0.91 | NPC1 (0.41) | EGFRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL4854721 | 0.86 | THRA (0.49) | EGFRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL28002486 | 0.85 | ALDH1A1 (0.44) | EGFRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL21777460 | 0.85 | EGFR (0.49) | EGFRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL11046518 | 0.84 | IAPP (0.43) | EGFRNPC1RAB9AHPGDMAPK1 | |
| SCHEMBL1629297 | 0.83 | HDAC3 (0.47) | EGFRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL201692 | 0.83 | NPC1 (0.57) | EGFRNPC1RAB9AHPGDMAPK1 | |
| SCHEMBL2230841 | 0.82 | EGFR (0.44) | EGFRNPC1RAB9AHPGDMAPK1 | |
| SCHEMBL7615859 | 0.82 | ALOX5 (0.43) | EGFRALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL18269260 | 0.82 | DGKA (0.47) | EGFRALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479784-B2 | Trisphenol derivative | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2025-11-25 | — | — | US | disclosed |
| US-20230234905-A1 | NOVEL TRISPHENOL DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2023-07-27 | — | — | US | disclosed |
| CN-115916734-A | Novel triphenol derivatives | 本州化学工业株式会社 | 2023-04-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479784-B2 | Trisphenol derivative | TTPA, CCNA2, CDK2AP2 | EGFR 4773/4885ALDH1A1 1566/4885NPC1 3783/4885 |
| US-20230234905-A1 | NOVEL TRISPHENOL DERIVATIVE | TTPA, CDK2AP2, CDKL2 | EGFR 4831/4885ALDH1A1 2038/4885NPC1 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.